Link: http://www.ncbi.nlm.nih.gov/pubmed/26171600

Am J Perinatol. 2015 Jul 14. [Epub ahead of print]
The Role of Surfactant Therapy in Nonrespiratory Distress Syndrome Conditions in Neonates.
Keiser A1, Bhandari V1.
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Abstract
While treatment of respiratory distress syndrome (RDS) with surfactant in premature neonates is well established, evidence for its use in non-RDS conditions, especially in the term neonate, has been less abundant. The last published review on a PubMed search was in 2001. In this review, we comprehensively and critically evaluated the evidence from the literature regarding the use of surfactant in specific non-RDS disorders in neonates. Surfactant administered as a bolus should be considered in the treatment of meconium aspiration syndrome with progressive respiratory failure. While controversial in congenital diaphragmatic hernia, it should be considered in Group B streptococcal pneumonia. As evidence evolves, we anticipate the broader application and more routine use of surfactant therapy for respiratory failure because of causes other than RDS.

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PMID: 26171600 [PubMed - as supplied by publisher]