Link: http://www.ncbi.nlm.nih.gov/pubmed/25783378

Pediatr Surg. 2015 Feb 20. pii: S0022-3468(15)00106-2. doi: 10.1016/j.jpedsurg.2015.02.026. [Epub ahead of print]
Long-term nutritional morbidity for congenital diaphragmatic hernia survivors: Failure to thrive extends well into childhood and adolescence.
Haliburton B1, Mouzaki M2, Chiang M3, Scaini V4, Marcon M5, Moraes TJ6, Chiu PP7.
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Abstract
BACKGROUND:
Failure to thrive (FTT) is well documented among congenital diaphragmatic hernia (CDH) survivors ≤3years of age, but its etiology, severity, and persistence beyond this age require further elucidation.

METHODS:
We conducted a single-center, retrospective study assessing anthropometrics, measured energy expenditure, and feeding tube (FT) use of 5-17 year olds in our multidisciplinary CDH clinic since January 2001. We stratified clinic visits based on age A: 5.0-6.9, B: 7.0-9.9, C: 10.0-14.9, and D: 15-17.9years.

RESULTS:
One hundred sixteen patients with 376 outpatient visits were reviewed. Anthropometric z-scores were below zero and did not vary across age cohorts. FTT and growth stunting each occurred in 14% of clinic visits. FTs inserted during infancy occurred in 25% of patients, and 60% remained by age 7 years. In cohort A, those with FTs were lighter and shorter than those without (p<0.05) but had similar BMIs. FTT incidence was higher in the FT group (p=0.020), but FTs were present in only 30% of those with FTT. Indirect calorimetry revealed increased energy expenditure in 58% of patients.

CONCLUSIONS:
Failure to thrive continues in long-term CDH survivors, FTs may not improve incidence of FTT. Increased energy expenditure may play a role.

Copyright © 2015. Published by Elsevier Inc.

KEYWORDS:
Calorimetry; Congenital diaphragmatic hernia; Enteral feeding tubes; Failure to thrive; Nutritional morbidity
PMID: 25783378 [PubMed - as supplied by publisher]