J Pediatr Surg. 2019 Jan 31. pii: S0022-3468(19)30056-9. doi: 10.1016/j.jpedsurg.2019.01.019. [Epub ahead of print]
Management preferences in ECMO mode for congenital diaphragmatic hernia.
Delaplain PT1, Jancelewicz T2, Di Nardo M3, Zhang L4, Yu PT5, Cleary JP6, Morini F7, Harting MT8, Nguyen DV9, Guner YS5; Study by ELSO CDH Interest Group.
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The purpose of this study was to identify management preferences that may exist in the care of infants with CDH receiving ECMO with emphasis on VV-ECMO.

A survey was created to measure treatment preferences regarding ECMO use in CDH. The survey was distributed to all APSA and ELSO/Euro-ELSO members via e-mail. Survey results were summarized using descriptive statistics.

The survey had 230 respondents. The survey participants were surgeons (75%), neonatologists/intensivists (23%), and "other" (2%). The mean annual center volume was 11.6(9.6) CDH cases, and the average number treated with ECMO was 4.5 (6.4) cases/yr. The most agreed upon criteria for ECMO initiation were preductal O2 saturation <80% refractory to ventilator manipulation and medical therapy (89%), oxygenation index >40 (80%), severe air-leak (79%), and mixed acidosis (75%). Over 60% of respondents agreed the VV-ECMO would be optimum for average risk neonates. However, this preference diminished as the pre-ECMO level of cardiac support increased. When asked about why each respondent would choose VA-ECMO over VV-ECMO, the responses varied significantly between surgeons and non-surgeons.

While there seem to be areas of consensus among practitioners, such as criteria for initiation of ECMO, this survey revealed substantial variation in individual practice patterns regarding the use of ECMO for CDH.

Qualitative, Survey.


Copyright 2019 Elsevier Inc. All rights reserved.

Congenital diaphragmatic hernia (CDH); Extracorporeal membrane oxygenation (ECMO); Practice patterns; Venoarterial; Venovenous

PMID: 30786989 DOI: 10.1016/j.jpedsurg.2019.01.019